The April 2023 edition of Anesthesiology features an article from our multidisciplinary team of cardiovascular, neuroscience, bioengineering, and biophysics researchers - authors Kimberly Howard-Quijano, MD, MS, FASE; Yuki Kuwabara, MD; Tomoki Yamaguchi, MD; Kenny M. Roman, PhD; Siamak Salavatian, PhD; Bradley K. Taylor, PhD; and Aman Mahajan, MD, PhD, MBA, with an accompanying editorial and podcast: