The April 2023 issue of Anesthesia & Analgesia (A&A) includes an inaugural high-impact bundle of six articles and infographics addressing distinct approaches to advancing perioperative medicine and broadening its scope in health care, accompanied by the editorial “Editorial Innovations in Practices and Technologies That Will Shape Perioperative Medicine” by our Chair, Aman Mahajan, MD, PhD, MBA, and Monty (Michael) Mythen, MBBS, MD, FRCA (Department of Anaesthesia and Critical Care, University College London, London, United Kingdom). In the coming months, A&A will release several podcasts and webinars related to this high-impact bundle.